By Christopher Rusk, LSW, LCADC, Manager, Recovery and Wellness Unit

Medication-assisted treatment (MAT) is an evidence-based approach that combines FDA-approved medications with counseling and behavioral therapies. These medications are carefully selected based on every patient’s unique need to support their recovery from substance use disorders. MAT can help manage cravings, stabilize brain function, and reduce the risk of relapse, which can make it a critical tool for maintaining long-term sobriety.

One of the biggest challenges in early recovery is post-acute withdrawal syndrome (PAWS) — a condition in which individuals experience lingering withdrawal symptoms such as anxiety, depression, fatigue, and cravings even after the acute withdrawal phase has ended. These symptoms can persist for weeks or months, increasing the risk of relapse. MAT can help manage these challenges by regulating brain chemistry and providing individuals with the stability needed to engage in therapy and build a strong foundation for recovery.

MAT for Alcohol Use Disorder 

MAT can support recovery by reducing cravings and minimizing the risk of relapse. The most commonly used medications for alcohol use disorder (AUD) include:

  • Naltrexone (oral or Vivitrol injection): Blocks the pleasurable effects of alcohol and reduces cravings, helping individuals avoid relapse. Vivitrol is a long-acting, monthly injection that provides continuous support.
  • Acamprosate: Helps restore chemical balance in the brain and reduces cravings, making it easier to maintain sobriety.
  • Disulfiram: Produces unpleasant effects when alcohol is consumed, acting as a deterrent to drinking.

MAT for Opioid Use Disorder 

Opioid use disorder (OUD) disrupts brain chemistry and can include a physical dependence, making it difficult to stop using without support. MAT plays a crucial role in reducing cravings and withdrawal symptoms while allowing individuals to focus on their recovery. Commonly used medications include:

  • Naltrexone (Vivitrol injection): Blocks the effects of opioids and prevents relapse. Unlike other medications for OUD, naltrexone does not activate opioid receptors and is not habit-forming.
  • Buprenorphine: A partial opioid agonist (a chemical that help activate a biological response in the body), buprenorphine reduces cravings and withdrawal symptoms without producing the same euphoric effects as full opioids. It can be prescribed in an office-based setting, allowing for greater accessibility.
  • Methadone: A long-acting opioid agonist that stabilizes brain chemistry, relieves withdrawal symptoms, and prevents cravings. It is available through specialized treatment programs.

How MAT Supports Long-Term Recovery

MAT is most effective when combined with counseling, peer support, and behavioral therapies. By managing cravings and reducing the symptoms of post-acute withdrawal syndrome, MAT allows individuals to focus on their recovery without the constant battle of withdrawal and relapse triggers. For many, these medications provide a bridge to long-term stability, helping patients engage in therapy, rebuild relationships, and regain control over their lives.

MAT and Valley Health System’s Recovery and Wellness Unit

Valley’s Recovery and Wellness Unit provides patients with withdrawal management, once known as detoxification, which is the process of effectively helping patients manage the physical and psychological symptoms that occur when they stop using or reduce their intake of a substance they have become dependent on. 

Each patient receives education on substance use disorder treatment options, group and individual therapy, and a personalized aftercare program. If a patient decides that MAT may be right for them, our program can initiate treatment or facilitate appointments with a provider in the community that can offer MAT follow-up in an office setting. 

To take the first step in your recovery process or to learn more, call 201-612-4949.

If you are in crisis, text or call 988. 

To learn more about medications used in treating substance-use disorders: samhsa.gov/medications-substance-use-disorders.