Advancing Cath Lab Results With FFRangio Coronary Physiology Assessment
Objective
To test whether FFRangio-guided treatment is non-inferior to conventional pressure wire-guided treatment in patients with coronary artery disease.
Eligibility
Adult patient ( ≥18 years old) presenting with CCS or NSTEACS with one or more study lesion(s) deemed appropriate (diameter stenosis 50-90%) for both pressure-wire and FFRangio physiologic assessment.
General Exclusion Criteria:
- Subject with ST-elevation (MI (STEMI) within 72 hours at time of study enrollment
- Prior coronary artery bypass graft (CABG) with patent grafts to the study vessel(s)
- Patients undergoing coronary physiologic assessment prior to possible CABG.
- The study vessel supplies a significant nonviable territory (e.g., prior transmural MI)
- Severe left sided valvular heart disease
- LVEF ≤ 30%
- Women who are pregnant or breastfeeding
- Patients with life expectancy <1 year life as estimated by treating physician.
- Subjects enrolled in other ongoing clinical studies.
NCT ID
NCT05893498
