Himanshu Gupta, MD

What techniques or procedures do you use in your practice?

The Valley Hospital is a leader in the use of novel noninvasive approaches for diagnosing cardiac disorders including FFR-CT for coronary artery disease, comprehensive coronary phenotyping using AI algorithms, myocardial mapping using cardiac MRI, and hemodynamic echo lab for valvular and structural heart disease. I am also trained in all aspects of cardiovascular imaging including cardiovascular CT, cardiovascular MRI, echocardiography, nuclear cardiology, and stress testing.

Describe some of your professional highlights.

I am an internationally recognized expert in advanced cardiovascular imaging. I have conducted research on coronary artery disease, atherosclerosis, valvular heart disease, diastolic function, right ventricular function, pulmonary hypertension, heart failure, COVID-19, and inflammation.

What would you like patients to know about your approach to care?

With a deep understanding of the latest clinical literature and evidence, I take pride in personalizing diagnostic and treatment approaches based on a holistic view of patient care. My unique combination of clinical, diagnostic, basic research, and cutting-edge technologies enables me to address even the most challenging clinical cases. I am passionate about promoting new paradigms for clinical diagnostics and care through innovation and collaborating with a wide range of researchers and clinicians at the intersection of medicine and technology, giving mea unique perspective on patient care.

Valley Medical Group providers accept these insurance plans

Aufan, M.R., Gupta, H., Sharifov, O.F., Perry, G.J., Denney Jr., T.S., & Lloyd, S.G. (2024). Non-invasively measured myocardial torsional modulus: Comparison to invasive evaluation of diastolic function. Journal of Cardiovascular Magnetic Resonance. https://doi.org/10.1016/j.jocmr.2024.101122

Alemany, V.S., Fortier, J., Gupta, H., Zaider, A., Grau, J., Burns, P., & Jabagi, H. (2024). A rare case of IgG4-related aortitis in the thoracic aorta mimicking an intramural hematoma: Navigating the diagnostic labyrinth. Journal of Cardiothoracic Surgery, 19(1), 599. https://doi.org/10.1186/s13019-024-03026-w

Castillero, E., Camillo, C., Erwin, W.C., Singh, S., Mohamoud, N., George, I., Eapen, E., Dockery, K., Ferrari, G., & Gupta, H. (2024). Somatostatin receptors in fibrotic myocardium. PLOS One, 19(7). https://doi.org/10.1371/journal.pone.0304813

Narula, J., Stuckey, T.D., Nakazawa, G., Ahmadi, A., Matsumura, M., Petersen, K., Mirza, S., Ng, N., Mullen, S., Schaap, M., Leipsic, J., Rogers, C., Taylor, C.A., Yacoub, H., Gupta, H., Matsuo, H., Rinehart, S., & Maehara, A. (2024). Prospective deep learning-based quantitative assessment of coronary plaque by ct angiography compared with intravascular ultrasound. European Heart Journal. Cardiovascular Imaging, jeae115. Advance online publication. https://doi.org/10.1093/ehjci/jeae115

Serruys, P.W., Kageyama, S., Pompilio, G., Andreini, D., Pontone, G., Mushtaq, S., La Meir, M., De Mey, J., Tanaka, K., Doenst, T., Teichgräber, U., Schneider, U., Puskas, J.D., Narula, J., Gupta, H., Agarwal, V., Leipsic, J., Masuda, S., Kotoku, N., … Onuma, Y. (2024). Coronary bypass surgery guided by computed tomography in a low-risk population. European Heart Journal. Advance online publication. https://doi.org/10.1093/eurheartj/ehae199

van Rosendael, A.R., Crabtree, T., Bax, J.J., Nakanishi, R., Mushtaq, S., Pontone, G., Andreini, D., Buechel, R.R., Gräni, C., Feuchtner, G., Patel, T.R., Choi, A.D., Al-Mallah, M., Nabi, F., Karlsberg, R.P., Rochitte, C.E., Alasnag, M., Hamdan, A., Cademartiri, F., … CONFIRM 2 investigators (2024). Rationale and design of the CONFIRM2 (Quantitative COroNary CT Angiography Evaluation For Evaluation of Clinical Outcomes: An InteRnational, Multicenter Registry) study. Journal of Cardiovascular Computed Tomography, 18(1), 11–17. https://doi.org/10.1016/j.jcct.2023.10.004

Girard, A.A., Denney, T.S., Gupta, H., Dell'Italia, L.J., Calhoun, D.A., Oparil, S., Sharifov, O.F., & Lloyd, S.G. (2023). Spironolactone improves left atrial function and atrioventricular coupling in patients with resistant hypertension. The International Journal of Cardiovascular Imaging. Advance online publication. https://doi.org/10.1007/s10554-023-03013-7

Tsai, T.Y., Kageyama, S., He, X., Pompilio, G., Andreini, D., Pontone, G., La Meir, M., De Mey, J., Tanaka, K., Doenst, T., Puskas, J., Teichgräber, U., Schneider, U., Gupta, H., Leipsic, J., Garg, S., C Revaiah, P., Stanuch, M., Skalski, A.,… Serruys, P.W. (2023). Feasibility and accuracy of real-time 3D-holographic graft length measurements. European Heart Journal Digital Health, 5(1), 101–104. https://doi.org/10.1093/ehjdh/ztad071

Nurmohamed, N.S., Cole, J.H., Budoff, M., Karlsberg, R.P., Gupta, H., Sullenberger, L.E., Quesada, C.G., Rahban, H., Woods, K.M., Uzzilia, J.R., Purga, S.L., Aquino, M., Hoffmann, U., Min, J.K., Earls, J.P., & Choi, A.D. (2024). Impact of atherosclerosis imaging-quantitative computed tomography on diagnostic certainty, downstream testing, coronary revascularization and medical therapy: The CERTAIN study. European Heart Journal Cardiovascular Imaging. Advance online publication. https://doi.org/10.1093/ehjci/jeae029

Fortier, J.H., Thapa, Y., Crean, A.M., Gupta, H., & Grau, J.B. (2023). Invasive management of hypertrophic cardiomyopathy with clinically important obstruction: Surgical myectomy is superior, but only when accessible. The Canadian Journal of Cardiology. Advance online publication. https://doi.org/10.1016/j.cjca.2023.11.040

Kageyama, S., Serruys, P.W., Kotoku, N., Garg, S., Ninomiya, K., Masuda, S., Morel, M., Taylor, C.A., Rogers, C., Thomsen, B., Pontone, G., Pompilio, G., Puskas, J.D., Doenst, T., La Meir, M., Teichgräber, U., Gupta, H., De Mey, J., Andreini, D., & Onuma, Y. (2023). Coronary computed tomography angiography-based SYNTAX score for comprehensive assessment of advanced coronary artery disease,
Journal of Cardiovascular Computed Tomography. https://doi.org/10.1016/j.jcct.2023.10.012.

Gupta, H., Spanopoulous, B., Lubat, E., Krinsky, G., Rutledge, J., Fortier, J.H., Grau, J.B., & Tayal, R. (2023). Real-world approach to comprehensive artificial intelligence-aided CT evaluation of coronary artery disease in 530 patients: A retrospective study. HELIYON, 9(9). https://doi.org/10.1016/j.heliyon.2023.e19974

Sharifov, O.F., Denney, T.S., Jr, Girard, A.A., Gupta, H., & Lloyd, S.G. (2023). Coronary artery disease is associated with impaired atrial function regardless of left ventricular filling pressure. International Journal of Cardiology, 131102. Advance online publication. https://doi.org/10.1016/j.ijcard.2023.05.052

Gamble, F. N., Aufan, M. R., Sharifov, O. F., Williams, L. J., Reighard, S., Calhoun, D. A., Gupta, H., Dell'Italia, L. J., Denney, T. S., Jr, & Lloyd, S. G. (2022). Diastolic function: Modeling left ventricular untwisting as a damped harmonic oscillator. Physiological Measurement, 43(2), 10.1088/1361-6579/ac4e6e.

Aryal, S. R., Calhoun, D. A., Coffin, M. D., Dell'Italia, L. J., Denney, T. S., Jr, Gaddam, K. K., Gupta, H., Lloyd, S. G., Sharifov, O. F., Siddiqui, M., Oparil, S., & Zhang, B. (2021). 

Spironolactone reduces aortic stiffness in patients with resistant hypertension independent of blood pressure change. Journal of the American Heart Association, 10(17).

Al-Mubarak, M., Evanochko, W. T., Gupta, H., Lloyd, S. G., Nath, H., Prejean, S. P., Redden, D., & Singh, S. P. (2021). An updated comparison of conventional coronary angiography with cardiac magnetic resonance imaging to diagnose the origin and proximal course of anomalous coronary arteries. The Journal of invasive cardiology, 33(9), E687–E693.

Aeron S., Agrawal A., Gupta A., & Gupta H. (2021, July). Trends in COVID-19 publications: Streamlining research using NLP and LDA. Frontiers in Digital Health. 1-24.

Gupta H., Hoffman D.H., Joon Hong S., & Laidlaw M.S. (2021, May). Impact of Epicardial Fat on Clinical Outcomes in COVID-19. Presented at the 70th annual Scientific Sessions of the American College of Cardiology, Atlanta, GA.

Sharifov OF, Murphy JM, Perry GJ, Tallaj J, Denney Jr. TS, Prabhu SD, Gupta H, Lloyd SG (2020). Echocardiographic diagnosis of left ventricular diastolic dysfunction: Impact of coronary artery disease. Echocardiography. 38(2): 197-206.